
Polynucleotides London Advanced Skin Rejuvenation
Polynucleotides Skin Rejuvenation at Hampstead Aesthetics, London

Polynucleotides for Skin Rejuvenation
If you’re looking for a powerful, regenerative skin treatment, polynucleotides could be exactly what your skin needs. At Hampstead Aesthetics, we offer cutting-edge polynucleotide injections using premium formulations like Ameela® and Plinest – designed to repair, hydrate, and revitalise your skin at a cellular level. Whether you’re struggling with dullness, fine lines, or under-eye hollowing, our polynucleotides London treatment helps stimulate collagen, reduce inflammation, and restore your natural glow – with clinically proven results.
At Hampstead Aesthetics Clinic in London, we’re committed to offering innovative, medically sound treatments that enhance skin health from the inside out. One such breakthrough in regenerative aesthetics is polynucleotides therapy — an advanced injectable treatment that encourages deep skin renewal at the cellular level.
Polynucleotides London can restore a youthful glow, improve skin integrity, and support natural collagen production — all without the overly “done” look associated with more traditional cosmetic procedures.
Polynucleotides London - Treatment Summary










What Are Polynucleotides and How Do They Work?
Polynucleotides are naturally occurring DNA fragments, often derived from marine sources, that act as biostimulators when injected into the skin. Rather than merely filling wrinkles or lines, they work beneath the surface to stimulate cellular repair, collagen synthesis, and hydration balance.
Unlike traditional dermal fillers, which add volume, polynucleotides enhance the skin's own regenerative capabilities, making them ideal for clients seeking a subtle yet powerful rejuvenation.
The Science Behind Polynucleotides Treatment for Skin Repair
These biologically active molecules activate fibroblasts — the skin cells responsible for producing collagen and elastin. Through this mechanism, they:
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Hydrate the skin by binding water molecules
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Promote tissue regeneration and cellular turnover
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Calm inflammation and neutralise oxidative stress
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Support microcirculation, improving skin nourishment
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Enhance overall skin firmness, texture, and luminosity
Clients typically notice improvements in under-eye brightness, reduced fine lines, better skin tone, and even improvement in acne-related scarring.

Where Can Polynucleotides Be Used?
Polynucleotide injections are incredibly versatile and suitable for multiple concerns. At our London clinic, we commonly treat:
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Under-eye hollowing and dark circles
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Fine lines around the mouth and cheeks
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Sagging or crepey skin on the neck and décolletage
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Acne scarring and post-inflammatory pigmentation
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Early signs of hair thinning
By tailoring the treatment to your skin’s needs, we help you achieve targeted rejuvenation with natural-looking results.

Evidence-Based Results from Polynucleotide Skin Boosters
Polynucleotides injections have been extensively researched and used in European and Asian medicine for over three decades, particularly in fields such as wound care and orthopaedics.
Recent dermatology studies have shown:
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Increased dermal density and improved elasticity in photoaged skin
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Measurable enhancement in skin hydration and texture
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Reduction in pigmentation and visible skin laxity
These treatments are CE-certified and meet strict European safety standards, offering a low-risk yet high-impact skin rejuvenation solution.
Top Benefits of Polynucleotide Skin Boosters
Clients visiting Hampstead Aesthetics Clinic for polynucleotide treatments can expect:
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Improved skin smoothness and elasticity
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Refined tone and luminosity
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Softening of fine lines, especially under the eyes
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Support for collagen production over several months
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Treatment of uneven pigmentation, dullness, and mild skin sagging
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Boosted skin quality on the face, neck, hands, and décolletage

The Polynucleotide London Treatment Journey at Hampstead Aesthetics
Step-by-Step: What to Expect from Your Polynucleotide Treatment
Your Polynucleotide London journey begins with a thorough consultation to assess your skin and determine the best treatment plan. On the day, we cleanse and prepare the skin, followed by precise injections using either a fine needle or cannula. The procedure takes around 30 minutes and is well-tolerated with minimal discomfort. There may be slight swelling or redness for 24–48 hours. Most clients return to normal activities immediately after. You’ll start to notice improved hydration and glow within 7–10 days, with ongoing collagen stimulation over several weeks.
Post Treatment Care and Recovery
After your polynucleotide injections, we recommend avoiding vigorous exercise, alcohol, and direct sun exposure for 24 hours. Do not apply active skincare like retinol or AHAs for three days post-treatment. Use gentle, hydrating products and SPF daily to support healing. Mild swelling or bruising is normal and typically subsides within 48 hours. For best results, follow your personalised treatment schedule and book maintenance sessions every 6–12 months.
Ameela vs. Plinest: Choosing the Right Polynucleotide for You
Looking for advanced skin regeneration in London? At Hampstead Aesthetics, we offer cutting-edge polynucleotide treatments in North London, including Ameela and Plinest polynucleotides — innovative injectables designed to improve hydration, texture, and elasticity.
Plinest, developed by Mastelli, is FDA approved, CE certified, and has been widely used across Europe since 2005. It’s a powerful polynucleotide skin booster, clinically proven to help with ageing, fine lines, scars, and skin quality loss. Alongside Ameela polynucleotides, these treatments deliver bio-regenerative results by stimulating collagen, repairing tissue, and enhancing skin vitality.
We serve clients across Finchley, Hampstead, and West Hampstead, and specialise in polynucleotides for skin regeneration. Whether you're searching for “polynucleotides London” or curious about the difference between leading brands, we’ll guide you through the best treatment for your skin during your consultation.
How Much Does Polynucleotide Treatment Cost in London?
At Hampstead Aesthetics, polynucleotide treatments start from £250 per session. For optimal results, we recommend a course of three to four sessions spaced 2–3 weeks apart, depending on your skin’s needs. Maintenance treatments every 6–12 months help sustain your results. During your consultation, we’ll create a bespoke plan tailored to your goals and budget.
I have had 2 out of the recommended 3 sessions of Polynucleotides and my under eyes look incredible! I cant wait for my next session to see my final results!
-Abbie D
Dr Chike recommended polynucleotides to me for my under eye area. My dark circles have finally disappeared!
Thankyou Hampstead Aesthetics for restoring my confidence!
-Sam
I have only had 1 session of polynucleotides on my face and neck so far and can already see amazing results!
-Bea
I had never heard of polynucleotides before Dr Chike recommended them to me so was a little sceptical to try them but i am so please i did.
My skin is glowing!
-Sarah J
Frequently Asked Questions About Polynucleotides
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How do Polynucleotides Rejuvenate Skin on a Cellular Level?
Polynucleotides are naturally occurring molecules of Salmon DNA nucleotides that promote skin regeneration and healing by stimulating cell growth and improving hydration. In aesthetic treatments, polynucleotides are injected into the skin to improve elasticity, texture, and firmness. These molecules activate the skin's natural repair mechanisms, encourage collagen production, and enhance tissue regeneration. This treatment is ideal for patients looking to address signs of ageing, such as fine lines, wrinkles, and skin laxity, without surgery. Interested in rejuvenating your skin with polynucleotides?
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How Long Do Polynucleotide Results Last?
Results from polynucleotide treatments generally last between 6 to 12 months, depending on the individual's skin type, lifestyle, and the extent of treatment. Skin hydration, elasticity, and firmness improvement can be maintained with follow-up sessions and a proper skincare routine. A 2021 study published in Journal of Cosmetic Dermatology highlighted the long-term benefits of polynucleotide injections in improving skin texture and promoting collagen synthesis.
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Cost of Polynucleotide Treatments in London
Polynucleotide treatment costs vary depending on the treatment area and the number of sessions required. On average, prices range from £300 to £600 per session. During your consultation, Dr Chike Emeagi will provide a personalised quote based on your specific skin goals and the extent of treatment needed.
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How Many Polynucleotide Sessions Will I Need?
Most patients benefit from a series of 3 to 4 sessions, spaced 2 to 4 weeks apart, to achieve optimal results. Maintenance treatments may be recommended every 6 to 12 months to sustain the effects. The exact number of sessions will depend on the condition of your skin and your desired outcome.
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Is Polynucleotide treatment painful?
The treatment is generally well-tolerated. A topical numbing cream is applied before the injections to ensure minimal discomfort. Most patients describe the feeling as a slight pinch or pressure during the procedure, which typically lasts about 30 minutes.
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Are There Any Side Effects from Polynucleotides?
Common side effects include mild swelling, redness, and bruising at the injection sites, which usually resolve within a few days. There may be temporary lumps or tenderness in rare cases, but these side effects are generally mild and temporary. A 2020 Clinical and Aesthetic Dermatology study confirmed that polynucleotide treatments are safe, with minimal risk of adverse reactions when performed by a trained practitioner.
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How Long Does a Polynucleotide Treatment Take?
The polynucleotide treatment typically takes around 30 to 45 minutes, depending on the area being treated. This makes it a convenient option for individuals looking for skin rejuvenation with minimal downtime.
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Can Polynucleotides Be Combined with Other Treatments?
Yes, polynucleotide treatments can be combined with other aesthetic procedures such as microneedling, PRP (platelet-rich plasma), or chemical peels to enhance the overall results. Combining treatments can further stimulate collagen production and skin regeneration, leading to even better outcomes. We'll discuss your treatment goals and recommend the best combination during your consultation.
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Who Is a Suitable Candidate for Polynucleotides London?
Polynucleotide treatments are suitable for improving skin elasticity, hydration, and texture. It is ideal for individuals experiencing fine lines, wrinkles, and skin laxity due to ageing or sun damage. This treatment is also great for those wanting to enhance their skin's natural radiance without undergoing invasive procedures.
Get in touch for Polynucleotides treatment in London with Dr Chike
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Is Polynucleotide Treatment Safe and FDA Approved?
Yes, polynucleotide treatments are considered safe when administered by a trained professional. The polynucleotides used are biocompatible and well-tolerated by the skin, with minimal risk of adverse reactions. Dr. Chiké Emeagi, with his extensive experience in regenerative medicine and aesthetics, ensures that the treatment is both safe and effective.
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Aftercare Advice for Polynucleotide Injections
After the procedure, avoid sun exposure, intense exercise, and rubbing or massaging the treated area for at least 24-48 hours. It's also important to avoid harsh skincare products like retinoids or exfoliants for a few days to allow the skin to heal properly. We'll provide you with detailed aftercare instructions to ensure the best possible results.
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Long-Term Skin Improvements with Polynucleotides London
Polynucleotides work by promoting cell regeneration, stimulating collagen production, and improving hydration within the skin. Over time, this leads to smoother, firmer skin with improved elasticity and texture. A 2021 study in the International Journal of Dermatology demonstrated that regular polynucleotide treatments significantly enhance skin quality and reduce the appearance of fine lines and wrinkles.
Don’t wait to experience the scientifically proven benefits of Polynucleotides. Contact Hampstead Aesthetics today to schedule your consultation. Let our team of experts help you achieve your skincare goals and reveal your natural beauty with this innovative treatment.
At Hampstead Aesthetics, we are dedicated to delivering high-quality, scientifically backed skincare treatments that provide exceptional results. Discover the rejuvenating benefits of Polynucleotides and embark on your journey to a more youthful, radiant complexion today.
Visit us in London and let us help you look and feel your best.
Medically reviewed by Dr. Chike Emeagi - MBBS MRCGP MSc MBA - Medical Director at Hampstead Aesthetics
Review date: 9 June 2025
Dr. Chike Emeagi has personally reviewed the content on this page for accuracy, safety, and clinical integrity.
This page reflects current best practices in regenerative injectables and skin rejuvenation.
































































































