Combining PDO Threads and PRP with Skin Boosters: Better Together?

Written by Dr. Chike Emeagi MBBS MRCS MRCGP MSc MBA

Combining PDO threads with other treatments like PRP and skin boosters is a comprehensive cosmetic procedure that can enhance skin tightening and hydration. It is crucial to consult experienced practitioners to ensure optimal results and minimize potential risks. These professionals can tailor treatments to individual needs, ensuring the best outcomes for patients. Combining PDO threads with other treatments involves various medical procedures to ensure optimal results.

Key Takeaway 💡

While PDO threads lift and firm the skin, combining them with regenerative treatments like skin boosters, PRP, or polynucleotides can dramatically enhance your results. These synergy treatments hydrate, brighten, and improve skin quality — making the lift look smoother, younger, and longer-lasting.

Combining these treatments can also lead to immediate improvement in skin appearance, providing a more pronounced and instant enhancement compared to treatments like Botox.

Introduction

PDO thread treatment is one of the most effective and safe procedures to lift sagging skin without surgery. The lifting effect provided by PDO lifting threads offers immediate improvements in facial contours and addresses sagging skin. Additionally, PDO threading has a long history of safe use with minimal risks, making it a safer alternative for many patients compared to facelift procedures. The combination of PDO lifting threads with other aesthetic treatments, such as Botox, can enhance overall results, effectively addressing fine lines and drooping skin.

But what if we told you that threads alone aren’t always enough to achieve the glowing, youthful look you want?

That’s where combination treatments come in. At Hampstead Aesthetics, we often pair thread lifts with skin boosters, PRP, and polynucleotides for next-level skin rejuvenation — all customised to your face, skin type, and goals.

Introduction to Aesthetic Treatments

Aesthetic treatments have become increasingly popular in recent years, with individuals seeking to enhance their natural beauty and achieve a more youthful appearance. One of the most revolutionary treatments in the world of aesthetics is the PDO thread lift, a non-surgical procedure that uses polydioxanone threads to lift and tighten sagging skin. This cutting-edge solution addresses skin laxity, fine lines, and wrinkles, providing a youthful appearance without the need for invasive surgery. PDO thread lifts can be combined with other aesthetic treatments such as dermal fillers and Botox to achieve even more dramatic results. These combinations allow individuals seeking natural beauty to benefit from a comprehensive approach to facial rejuvenation, enhancing both the structure and quality of the skin.

Understanding PDO Thread Lift

A PDO thread lift is a revolutionary treatment that utilizes polydioxanone threads to stimulate collagen production and improve skin texture. This innovative procedure involves the insertion of PDO threads into the subcutaneous layer of the skin, which helps to lift and tighten sagging skin. Unlike traditional surgical facelifts, PDO thread lifts are minimally invasive, offering a natural-looking and youthful appearance with minimal downtime. After achieving the desired skin tightening, any excess threads are cut off to ensure optimal results.

The threads used in this treatment are made of a biodegradable material that is gradually absorbed by the body over time, leaving behind a network of collagen fibers. This process not only lifts the skin but also promotes natural collagen production, enhancing skin elasticity and reducing the appearance of fine lines and wrinkles. PDO threads offer various aesthetic benefits, including long-lasting results that can enhance collagen production and improve facial structure. PDO thread lifts can address various skin concerns, including skin laxity, making it an ideal treatment for individuals seeking a non-surgical facelift.

Types of PDO Thread Lifts

There are several types of PDO thread lifts available, each designed to target specific areas of the face and body. For instance, the PDO thread lift for the lower face is particularly effective in addressing marionette lines and nasolabial folds, providing a lifted and rejuvenated appearance. Another popular option is the PDO thread lift for the eyebrows, which enhances the shape and definition of the brows, giving a more youthful and alert look. Additionally, PDO threads can be used to add volume to the cheeks and other areas of the face, offering a natural lift and fullness. These versatile threads can be tailored to meet the unique needs of each patient, ensuring that every treatment delivers optimal results.

Why Combine PDO Threads with Other Skin Treatments?

Threads offer structure — but for patients with:

• Dry, dull or thin skin

• Fine lines or crepey texture

• Early signs of volume loss

• Post-inflammatory pigmentation or sun damage

…it’s essential to boost skin quality alongside tightening. Combination therapies treat the skin from both inside and out, stimulating collagen production and improving:

• Hydration

• Collagen density

• Elasticity

• Healing

Combination therapies can also help restore lost volume and improve skin elasticity, leading to smoother, more elastic skin by reducing lines and wrinkles.

These treatments help the body produce collagen, leading to enhanced skin elasticity and firmness.

🧪 *A 2025 multicentre trial showed that combining PDO threads with skin boosters and PRP increased patient satisfaction by 39% and collagen thickness by 41% after 12 weeks.*¹

How Combination Therapy Works

Combination therapy is a popular approach in aesthetics, where multiple treatments are used in conjunction with one another to achieve optimal results. PDO thread lifts can be combined with Botox, dermal fillers, and other treatments to provide a comprehensive approach to facial rejuvenation. For example, Botox can be used to relax the muscles that cause wrinkles, while PDO threads can be used to lift and tighten the skin. This combination can provide natural-looking results and can be tailored to individual aesthetic goals. By addressing both the structural and surface aspects of aging, combination therapy ensures a more harmonious and youthful appearance.

Top Treatments to Combine with PDO Threads

1. Skin Boosters (e.g. Profhilo, Seventy Hyal)

These injectable hydrators improve:

• Glow and radiance

• Fine lines and laxity

• Skin density and smooth texture

💧 Best paired 2–4 weeks before or after thread lift for smoother integration and faster recovery.

2. PRP (Platelet-Rich Plasma)

Your own growth factors are used to:

• Accelerate healing post-thread

• Improve tone, texture, and firmness

• Aid in tissue repair and rejuvenation

• Reduce swelling and downtime

Combining PRP with PDO threads can also provide an instant facial lift, making it an appealing option for those seeking immediate results without the financial burden or risks associated with surgical facelifts.

🩸 Especially helpful for under-eyes, necks, or mature skin types.

3. Polynucleotides (e.g. Nucleofill, Plinest)

These DNA fragments:

• Restore skin thickness and elasticity

• Calm inflammation

• Improve long-term hydration and repair

• Promote collagen stimulation for long-term skin rejuvenation

🧬 Ideal for skin stressed by ageing, sun exposure, or pollution. Often used in tear trough, cheeks, or neck alongside threads.

The Benefits of Combining PDO Threads with Skin Boosters or PRP

Safety and Risks of Combination Therapy

Combining PDO threads with other aesthetic treatments, such as Botox and dermal fillers, can be a safe and effective way to achieve enhanced skin texture and a more youthful appearance. Botox relaxes the muscles responsible for causing wrinkles, including crow's feet, and can be combined with PDO threads for enhanced results. When combined with PDO threads, hyaluronic acid-based filler injections can provide dramatic yet natural-looking rejuvenation. However, as with any medical procedure, there are potential risks and side effects associated with combination therapy. These may include allergic reactions, visible sutures, and uneven pigmentation.

To minimize these risks, it is essential to choose an experienced practitioner who has a thorough understanding of the treatment site and the appropriate layer of skin to insert the PDO threads. Minimally invasive procedures require proper client analysis by a competent practitioner for optimal results. A comprehensive consultation is necessary to discuss the individual’s aesthetic goals and determine the best course of treatment. By taking the necessary precautions and choosing a qualified practitioner, individuals can enjoy the benefits of combination therapy, including a more natural-looking and long-lasting result.

Ideal Candidate for Combination Treatments

Combination therapy is ideal if you:

• Are aged 35–65 and seeking non-surgical rejuvenation

• Want both lift and skin improvement

• Have dull, dehydrated, or sun-damaged skin

• Need to treat multiple layers of ageing (structure + skin)

Most patients typically undergo these combination treatments every 12 to 18 months to maintain their results.

Planning and Evaluation for Combination Therapy

Planning and evaluation are crucial steps in combination therapy, as they help to determine the best course of treatment and ensure that the individual’s aesthetic goals are met. During the planning stage, the practitioner will assess the individual’s facial structure, skin texture, and skin laxity to determine the most effective treatment plan. This thorough assessment ensures that the chosen treatments will work synergistically to achieve the desired results.

The practitioner will also discuss the individual’s medical history, including any previous treatments or procedures, to ensure that the chosen treatment is safe and effective. Evaluation is an ongoing process that continues throughout the treatment, as the practitioner monitors the individual’s progress and makes any necessary adjustments to the treatment plan. By taking a thorough and individualized approach to planning and evaluation, practitioners can help individuals achieve a more youthful and natural-looking appearance with combination therapy.

Recovery and Aftercare

One of the benefits of PDO thread lifts is the minimal downtime required after the procedure. Most patients can return to their normal activities immediately, although some swelling and bruising may occur. To ensure optimal results and minimize the risk of complications, it is essential to follow a proper aftercare routine. This may include avoiding strenuous activities, keeping the treatment site clean, and avoiding excessive sun exposure. Experienced practitioners can provide personalized aftercare instructions and guidance to ensure a smooth and successful recovery. By adhering to these guidelines, patients can enjoy the full benefits of their PDO thread lift with minimal disruption to their daily lives.

Long-Term Results

PDO thread lifts can provide long-term results, with some patients experiencing benefits for up to two years or more after the procedure. The treatment stimulates collagen production at a cellular level, which can lead to enhanced skin texture and elasticity. To maintain optimal results, regular maintenance treatments may be necessary, although the frequency of these treatments will depend on individual factors such as skin type and aesthetic goals. With proper care and maintenance, PDO thread lifts can provide a youthful and lifted appearance that can last for years to come. This long-lasting effect makes PDO thread lifts a valuable investment in one’s aesthetic journey.

FAQs: PDO Threads with Skin Boosters and PRP

🧠 Final Thoughts: Are Combination Treatments Worth It?

✨ If you’re looking to lift, tighten and glow all at once, the outcomes achieved by combining PDO threads with supportive treatments like skin boosters or PRP may be the most powerful option. Additionally, combining PDO threads and Botox can address both sagging skin and fine lines simultaneously, offering a comprehensive approach to facial rejuvenation.

It’s not just about how high you lift — it’s also about how healthy and radiant your skin looks when you do.

🔗 Book your bespoke combination rejuvenation plan at Hampstead Aesthetics today and discover your full-face glow.

Future of Combination Therapy

The future of combination therapy looks promising, as advancements in technology and the development of new treatments continue to expand the possibilities for aesthetic procedures. One of the most exciting developments in combination therapy is the use of PDO lifting threads with other treatments, such as Botox and dermal fillers, to achieve a more comprehensive and long-lasting result. PDO threads offer various aesthetic benefits, including long-lasting results that can enhance collagen production and improve facial structure. The results of PDO threads can last from 1 to 2 years, while Botox results typically last about 3 to 4 months, allowing for tailored treatment plans based on patient needs.

Additionally, the use of cutting-edge solutions, such as polydioxanone threads, is helping to revolutionize the field of aesthetics and provide individuals with a more natural-looking and youthful appearance. As the demand for non-invasive and minimally invasive procedures continues to grow, combination therapy is likely to become an increasingly popular choice for individuals seeking to enhance their appearance.

With its ability to stimulate collagen production, improve skin texture, and provide a more youthful appearance, combination therapy is an exciting and innovative treatment option that is sure to shape the future of aesthetics.

💡 Why Choose Hampstead Aesthetics for Combination Thread Plans?

👨‍⚕️ Dr. Chike Emeagi MBBS, MRCS, MRCGP, MSc, MBA is one of the UK’s leading experts in combination aesthetics, trusted by patients and professionals alike.

Why Patients Trust Our Clinic:

• ✅ Full mapping and staging for thread and PRP/booster plans

• ✅ CE-certified and FDA-cleared treatments only

• ✅ Custom protocols for every skin type and age group

• ✅ Beautiful, natural results every time

📚 Scientific References⁽¹⁾ J Cosmet Dermatol. 2025;24(3):198–206.⁽²⁾ Aesthetic Plast Surg. 2024;48(1):44–52.⁽³⁾ Dermatol Surg. 2023;49(2):S122–S128.