Obagi Rx Tretinoin 0.05% Cream Serum

Prescription-strength results for acne, blemishes, and early ageing.

Obagi Rx Tretinoin 0.05% Cream Serum is a dermatologist-grade treatment designed to address acne, texture irregularities, and early signs of ageing. With a mid-strength concentration, it offers a balance of visible results and manageable tolerance.

What It Is

A fragrance-free, prescription-only cream containing 0.05% tretinoin—an active form of Vitamin A. It works deep within the skin to boost cell turnover, unclog pores, and stimulate collagen production.

Key Benefits

Treats mild to moderate acne and prevents future breakouts
Improves skin texture and clarity
Diminishes the appearance of fine lines
Supports long-term collagen production
Ideal step-up for those experienced with lower concentrations

Active & Other Ingredients

Active: Tretinoin 0.05%
Inactive: stearic acid, isopropyl myristate, polyoxyl 40 stearate, stearyl alcohol, xanthan gum, sorbic acid, butylated hydroxytoluene, purified water

How to Use

Apply a pea-sized amount once daily in the evening
Use on clean, dry skin after waiting 20–30 minutes post-cleansing
Avoid the eye area, nostrils, and lips
Always follow with moisturiser and SPF in the morning

Who It’s For

Suitable for acne-prone and ageing skin
Recommended for those who have already used 0.025% tretinoin or other retinoids
Works well for normal, oily, or combination skin types

Safety & Precautions

Temporary redness, peeling, or dryness is common—ease in gradually
Use sunscreen daily to protect sensitised skin
Not for use during pregnancy or breastfeeding
Avoid waxing and harsh exfoliants during use

Storage

Store at room temperature (15°C–25°C / 59°F–77°F)
Protect from excessive heat and light
Keep tightly closed when not in use

FAQs

Q: How does 0.05% compare to 0.025%?
A: It’s stronger and may produce faster results, but with increased chance of irritation.

Q: Can I use it every night?
A: Start with 2–3 times weekly, then increase as tolerated.

Q: Can I combine it with Vitamin C?
A: Yes, but use Vitamin C in the morning and tretinoin at night.