Obagi Rx Tretinoin 0.1% Cream Serum delivers prescription-level performance for targeting acne, early ageing, and skin texture concerns. With the highest strength available in this range, it offers more significant results—best for those who’ve already built tolerance with lower strengths.

What It Is
A fragrance-free, prescription-only topical cream containing 0.1% tretinoin (all-trans retinoic acid). This potent retinoid enhances cell turnover, clears clogged pores, promotes collagen production, and improves skin clarity.

Key Benefits

• Treats moderate acne and prevents new breakouts
• Dramatically refines skin texture and tone
• Reduces appearance of fine lines and pigmentation
• Encourages long-term collagen support
• Ideal for experienced retinoid users seeking faster, deeper action

Active & Other Ingredients

• Active: Tretinoin 0.10%
• Inactive: Stearic acid, isopropyl myristate, polyoxyl 40 stearate, stearyl alcohol, xanthan gum, sorbic acid, butylated hydroxytoluene, purified water

How to Use

• Apply a pea-sized amount to clean, dry skin once every 2–3 nights
• Wait at least 20–30 minutes after cleansing before applying
• Avoid eyes, lips, and nostrils
• Gradually build up frequency as tolerated
• Always follow with a gentle moisturiser and morning SPF

Who It’s For

• Individuals with resistant moderate acne or significant texture issues
• Those who have already used 0.05% tretinoin or other retinoids
• Suitable for normal, oily, or combination skin types

Safety & Precautions

• Initial redness, peeling, dryness, or sensitivity may occur
• Introduce gradually—avoid daily use until skin adapts
• Daily broad-spectrum SPF is essential due to increased sun sensitivity
• Not recommended during pregnancy or breastfeeding
• Avoid waxing, abrasive scrubs, and chemical exfoliants while using

Storage

• Store at room temperature (15 °C–25 °C / 59 °F–77 °F)
• Protect from direct sunlight and high heat
• Keep bottle tightly closed when not in use

FAQs

Q: How does it compare to 0.05%?
A: It’s twice the strength for faster results, but with higher irritation potential.

Q: Can I use it nightly?
A: Start 2–3 nights per week and increase frequency as your skin tolerates.

Q: Can I pair it with Vitamin C?
A: Yes. Use Vitamin C in the morning and tretinoin at night on alternate nights until your skin adjusts.

Clinician Endorsement
Recommended by Dr. Chike Emeagi for patients needing advanced acne and anti-ageing treatment under expert supervision.