Polynucleotides for Skin Rejuvenation at Hampstead Aesthetics, London

Revitalize your skin with the power of Polynucleotides at Hampstead Aesthetics

Restore your skin’s natural glow with Polynucleotide treatment at Hampstead Aesthetics. This advanced therapy rejuvenates from within, smoothing fine lines, improving skin texture, and delivering deep, long-lasting radiance for a healthier, more youthful complexion.

What are Polynucleotides?

Polynucleotides are naturally occurring molecules composed of long chains of nucleotides, which are the building blocks of DNA and RNA. These molecules are rich in growth factors and have remarkable regenerative properties. When used in skin rejuvenation, Polynucleotides stimulate collagen production, enhance skin elasticity, and promote overall skin regeneration.

In aesthetic treatments, polynucleotides are highly purified molecules typically derived from salmon DNA, known for their excellent safety and biocompatibility. They work by stimulating the skin’s natural repair processes, improving elasticity, reducing fine lines, and enhancing overall skin tone and texture. Polynucleotide treatments are especially effective for clients seeking natural-looking, long-lasting rejuvenation with minimal downtime.

Service Details

Proudly serving clients from Hampstead, Swiss Cottage, Camden, Primrose Hill, Belsize Park, St John’s Wood, Queen’s Park, and Finchley Road

Opening Hours

Mon - Fri: 10am to 7pm Sat: 9am to 6pm

Price

£53 per session

Schedule

Monday–Saturday, 10 AM – 7 PM

The Science Behind Polynucleotides Treatment for Skin Repair

When injected into the skin’s dermal layers, Polynucleotides stimulate the production of collagen and elastin, the essential proteins responsible for maintaining skin’s strength, elasticity, and firmness.

 

This encourages tissue regeneration, leading to smoother, plumper skin and a noticeable reduction in fine lines, wrinkles, and skin laxity.

 

Polynucleotides offer a safe, non-invasive alternative to more aggressive skin treatments, making them ideal for clients seeking natural-looking rejuvenation.

 

Derived from highly purified salmon DNA, these biostimulating molecules work at a cellular level to repair damaged tissue, boost hydration, and improve overall skin texture and tone.

 

Over time, they help restore skin vitality, reduce signs of ageing, and support a healthier, more radiant complexion, with minimal downtime and excellent tolerance across all skin types.

Benefits of Polynucleotides

Research indicates that Polynucleotides can significantly enhance collagen production, showing an increase of up to 47% in just 23 days. Additionally, they help thicken the epidermis, improving its health by 52% over the same period. 

With a variety of beneficial applications, Polynucleotides offer remarkable skin rejuvenation effects:

  • Boosts Collagen and Elastin Production:

 

Polynucleotides stimulate the natural production of collagen and elastin, essential proteins that improve skin elasticity and firmness. This leads to a noticeable reduction in the appearance of wrinkles and sagging skin, delivering a more youthful and refreshed complexion.

  • Restores Hydration and Volume:

By enhancing skin hydration and restoring volume, Polynucleotides help tackle skin dryness and thinning, resulting in a plump, more revitalised appearance.

  • Reduces Inflammation:

The anti-inflammatory effects of Polynucleotides help soothe the skin, reducing redness and irritation, and contributing to an overall healthier and calmer complexion.

  • Protects Against Environmental Damage

Polynucleotides help protect the skin from environmental stressors, especially sun damage, promoting the skin’s natural defences and supporting long-term skin health.

  • Minimal Downtime

One of the key advantages of Polynucleotides is that they offer minimal downtime compared to other injectable treatments. You can resume your daily activities shortly after your session.

 

How Does Polynucleotides Work?

Polynucleotides are rich in growth factors that stimulate the production of collagen and elastin, two key proteins that give the skin its strength, elasticity, and firmness.

 

When injected into the skin’s dermal layers, Polynucleotides directly interact with fibroblasts (the cells responsible for collagen production), triggering a regenerative response that enhances skin texture, tone, and overall structure.

 

As the treatment stimulates tissue regeneration, it helps to repair damaged skin, smooth out fine lines, and improve skin laxity, leading to a visibly firmer, plumper, and more youthful appearance.

Ameela vs. Plinest: Choosing the Right Polynucleotide

At Hampstead Aesthetics, we offer advanced polynucleotide treatments in North London, featuring Ameela and Plinest polynucleotides, innovative injectables that enhance hydration, texture, and elasticity.

 

Plinest, developed by Mastelli, is FDA-approved, CE-certified, and has been widely used across Europe since 2005. This powerful polynucleotide skin booster is clinically proven to address signs of aging, fine lines, scars, and skin quality loss.

 

When combined with Ameela polynucleotides, these treatments provide bio-regenerative effects by stimulating collagen production, repairing tissue, and improving skin vitality.

How Much Does Polynucleotide Treatment Cost in London?

At Hampstead Aesthetics, polynucleotide treatments start from £300 per session. For optimal results, we recommend a course of three to four sessions spaced 2–3 weeks apart, depending on your skin’s needs.

 

Maintenance treatments every 6–12 months help sustain your results. During your consultation, we’ll create a bespoke plan tailored to your goals and budget.

Polynucleotide Treatment Areas

At Hampstead Aesthetics, we offer Polynucleotide treatments to target various skin and hair concerns with exceptional results. Here are some of the key treatment areas:

  • Rejuvenation of Aged Skin

Polynucleotides are highly effective in reducing fine lines and wrinkles by stimulating the production of collagen and elastin, promoting smoother, firmer, and more youthful skin.

 

  • Preventative Treatment for Younger Skin

For younger skin, Polynucleotides can be used as a preventative measure, slowing down the natural ageing process by enhancing skin vitality and boosting elasticity to help maintain a youthful appearance.

 

  • Rehydration for Dull Skin

Whether you’re dealing with dry skin or a dull complexion, Polynucleotides provide deep hydration, revitalising the skin and restoring its natural glow.

 

  • Treatment for Dark Circles

Polynucleotides offer an effective alternative to tear trough fillers for those seeking to reduce the appearance of dark circles around the eyes. The treatment nourishes the delicate skin under the eyes, brightening and refreshing the area.

 

  • Strengthening Delicate Skin Areas

Polynucleotides can strengthen and rejuvenate the delicate skin around the eyes and mouth, which are often the first areas to show signs of ageing and skin laxity.

 

  • Reducing Inflammation and Treating Skin Conditions

With their anti-inflammatory properties, Polynucleotides are ideal for managing conditions such as rosacea, reducing redness and inflammation while helping to calm irritated skin.

 

  • Treating Hyperpigmentation, Sun Damage, Scarring, and Stretch Marks

Polynucleotides can address various pigmentation issues, including sun damage, hyperpigmentation, and acne scars. They also aid in improving the appearance of stretch marks, promoting healthier and more even skin tone.

 

  • Alopecia and Hair Loss Treatment

When used in hair restoration, Polynucleotides stimulate the scalp and hair follicles, encouraging hair growth and improving density, making them an effective treatment for conditions like alopecia and thinning hair.

  • Enhancing Other Aesthetic Treatments

Polynucleotides work synergistically with other aesthetic treatments, including anti-wrinkle injections and dermal fillers, boosting their effectiveness and extending the longevity of results.

Polynucleotide Treatment​ Procedure

We provide a personalised Polynucleotide treatment designed to rejuvenate the skin and promote healing at the cellular level. The procedure is minimally invasive and delivers impressive results with little to no downtime. 

Here’s what you can expect during your treatment:

  • Consultation and Assessment

Before starting the treatment, you’ll have a detailed consultation with one of our skilled practitioners. During this session, we will assess your skin condition, discuss your goals, and determine whether Polynucleotide treatment is the right solution for your needs. Our expert team will tailor the treatment to suit your specific concerns, whether it’s fine lines, skin laxity, or hair restoration.

  • Preparation and Numbing

Once we’ve confirmed your treatment plan, the area to be treated will be thoroughly cleansed. If necessary, a topical numbing cream will be applied to ensure comfort during the procedure. The cream takes a few minutes to take effect, allowing for a smooth and pain-free experience.

  • Injection of Polynucleotides

After numbing, a fine needle will be used to inject the Polynucleotides directly into the dermal layers of the skin or targeted areas (such as around the eyes, mouth, or scalp). The treatment typically takes 30 to 60 minutes, depending on the number of areas being treated. The Polynucleotides work by stimulating collagen and elastin production, encouraging skin regeneration and improving texture.

  • Post-Treatment Care

Once the procedure is completed, the treated areas may appear slightly red and swollen, but this is temporary and should subside within a few hours. You’ll be given aftercare instructions to follow, which may include avoiding sun exposure, refraining from excessive heat, and keeping the area clean.

  • Results and Follow-Up

After treatment, you can resume your daily activities with little to no downtime. Polynucleotide treatments work gradually, with noticeable improvements in skin tone, texture, and elasticity starting to show within a few weeks. Full results typically appear after 3 to 6 months, with continued improvement as collagen production is stimulated.

 

Regular treatments or maintenance sessions may be recommended depending on your skin’s needs, to help maintain and enhance the rejuvenating effects.

Polynucleotide Post Treatment Care and Recovery

We ensure that every aspect of your Polynucleotide treatment is carried out with care, and post-treatment is just as important for achieving optimal results. Here’s what to expect and how to care for your skin following the procedure:

  • Immediate Aftercare

After your Polynucleotide treatment, you may experience mild redness, swelling, or a slight tingling sensation at the treatment site. These effects are temporary and should subside within a few hours to a day.

  • Avoid Touching the Treated Area

It’s important to avoid touching, rubbing, or massaging the treated areas for at least 24 hours to prevent any potential irritation or infection. 

  • Keep the Treated Skin Clean

Keep the treated area clean by gently washing with a mild, non-irritating cleanser. Avoid using any harsh skincare products, such as exfoliants or retinoids, for at least 5-7 days after treatment to prevent irritation.

  • Sun Protection

Avoid direct sun exposure for 48-72 hours after your treatment, and wear a high-SPF sunscreen to protect the treated area from UV damage.

  • No Heat or Intense Activities

For the first 24-48 hours, it’s best to avoid activities that may induce sweating or cause excessive heat on the skin, such as saunas, steam rooms, or vigorous exercise.

  • Hydration is Key

After your treatment, maintaining adequate hydration is essential. Drink plenty of water to help your body support the healing process.

  • Follow-Up Appointments

We recommend follow-up appointments to assess your progress and discuss any further treatments or maintenance options..

  • Recovery Timeline

The recovery process after Polynucleotide treatment is typically quick, with minimal downtime. Most clients can resume their normal activities the day after the procedure, with improvements becoming noticeable within a few weeks. Full results usually develop over the next 3-6 months as the skin continues to regenerate.

Why Choose Hampstead Aesthetics for Polynucleotide Treatment in London?

At Hampstead Aesthetics, we offer Polynucleotide treatments under the expertise of Dr. Chiké Emeagi, a leader in skin rejuvenation.

 

Using FDA-approved technology, we target skin concerns like fine lines, wrinkles, and skin laxity, stimulating collagen and elastin production for firmer, smoother skin.

 

We take a personalised approach, tailoring each treatment to your unique needs. With minimal downtime and long-lasting results, our clinic ensures that you receive the highest standard of care for youthful, revitalised skin.

 

Choose Hampstead Aesthetics for Polynucleotide treatment, and experience the best in advanced skin care and rejuvenation.

FAQs About Polynucleotides

  • What is the difference between Polynucleotides and skin-booster injections?

Polynucleotides are a unique form of skin rejuvenation treatment that work by stimulating collagen and elastin production to improve skin elasticity, texture, and firmness.

 

Unlike traditional skin boosters, which focus primarily on hydration, Polynucleotides promote deeper regenerative effects and address skin concerns like fine lines, wrinkles, and skin laxity.

  • How do Polynucleotides differ from other aesthetic treatments like fillers or anti-wrinkle injections?

While fillers add volume to the skin and anti-wrinkle injections relax facial muscles to reduce wrinkles, Polynucleotides work on a cellular level, promoting the regeneration of the skin by stimulating collagen and elastin production.

 

This makes them an excellent treatment for skin rejuvenation and improving overall skin health, rather than simply targeting wrinkles or volume loss.

  • What skin concerns can Polynucleotide treatments address?

Polynucleotide treatments are versatile and can address a variety of skin concerns, including fine lines, wrinkles, skin laxity, uneven skin texture, sun damage, hyperpigmentation, and scarring.

 

It is also effective for treating dark circles, stretch marks, and acne scars, and can be used to improve hair growth in individuals with hair thinning or alopecia.

  • Is the Polynucleotide treatment painful?

Most patients find the treatment to be relatively painless. A mild tingling or pricking sensation is usually felt during the procedure.

 

To ensure comfort, we apply numbing cream before the injections, making the treatment well-tolerated for most individuals.

  • How long do the results of Polynucleotide treatments last?

The results of Polynucleotide treatment can last 6 months to a year, depending on individual skin types and maintenance. Regular follow-up treatments can help sustain and enhance the effects, especially for long-term rejuvenation and skin health.

  • Can Polynucleotides be combined with other aesthetic procedures?

Yes, Polynucleotides can be safely combined with other treatments, such as dermal fillers, anti-wrinkle injections, and microneedling, to enhance overall results.

 

Polynucleotides complement these treatments by improving skin quality and stimulating natural regeneration, boosting the longevity and effectiveness of other procedures.

  • What is the pre-treatment advice before Polynucleotides?

Before your Polynucleotide treatment, we advise that you avoid sun exposure for at least 48 hours, and refrain from using exfoliating or harsh skincare products for a few days.

 

Additionally, you should avoid alcohol and blood-thinning medications (like aspirin) for 24 hours before the procedure. These precautions ensure optimal results and minimise any risk of irritation or complications.

 

  • What is the pre-treatment advice before Polynucleotides?

Before your Polynucleotide treatment, we advise that you avoid sun exposure for at least 48 hours, and refrain from using exfoliating or harsh skincare products for a few days.

 

Additionally, you should avoid alcohol and blood-thinning medications (like aspirin) for 24 hours before the procedure. These precautions ensure optimal results and minimise any risk of irritation or complications.

  • What’s the Difference Between Plinest and Ameela?

Both Plinest and Ameela are advanced polynucleotide injectables designed to improve skin quality, but they have slightly different benefits and formulations:

  • Plinest:

One of the original polynucleotide brands, Plinest is known for its ability to repair damaged skin, stimulate fibroblasts, and improve hydration and elasticity. It’s often chosen for treating fine lines, acne scarring, and delicate areas like the under-eye. It works especially well for skin that has lost its firmness or needs regenerative support.

  • Ameela (formerly known as Nucleofill Eyes):

Ameela is formulated to target puffiness, dark circles, and skin laxity around the eyes. It’s slightly thicker than Plinest, providing more structural support. This makes it ideal for under-eye rejuvenation, where it improves firmness, reduces shadows, and restores a refreshed look without adding volume.

At Hampstead Aesthetics, we’ll choose the right polynucleotide product based on your skin’s needs and the treatment area — ensuring safe, subtle, and effective results.

Before and After Polynucleotides Treatment

Our clinic prioritises patient safety, natural-looking results, and ethical care, making it a trusted choice for individuals seeking subtle, refined enhancements in a professional setting.

Book Your Consultation

Unsure where to start? Schedule a personalised consultation with Dr. Chiké or a member of the team to explore your options

Book Your Consultation

Unsure where to start? Schedule a personalised consultation with Dr. Chiké or a member of the team to explore your options